OHDSI Center Events

CBER BEST Seminar Series: KEEPER: Standardized structured data from electronic health records as an alternative to chart review for case adjudication and phenotype evaluation

Anyone can register and join for free.

Topic

KEEPER: Standardized structured data from electronic health records as an alternative to chart review for case adjudication and phenotype evaluation

Speaker

Dr. Anna Ostropolets

Description

Chart review as the current gold standard for phenotype evaluation cannot support observational research at scale. It is expensive, time-consuming, and variable. In this talk, we will discuss how structured data can support efficient phenotype evaluation and case adjudication. We will show Knowledge-Enhanced Electronic Patient Profile Review system (KEEPER) that extracts a patient’s structured data elements relevant to a given phenotype and presents them in a standardized fashion that follows clinical reasoning principles.

We will discuss its performance compared to manual chart review for four conditions (diabetes type I, acute appendicitis, end stage renal disease and chronic obstructive lung disease) and will demonstrate that it can achieve similar accuracy and higher inter-rater reliability compared to chart review at a fraction of time.