OHDSI Center Events

CBER BEST Seminar Series: Avoidable and bias-inflicting methodological pitfalls in real-world studies of medication safety and effectiveness

Anyone can register and join for free.

Topic

Avoidable and bias-inflicting methodological pitfalls in real-world studies of medication safety and effectiveness

Speaker

Dr. Katsiaryna Bykov
Assistant Professor of Medicine at Harvard Medical School
Associated Epidemiologist in the Division of Pharmacoepidemiology and Pharmacoeconomics at Brigham and Women’s Hospital

Description

Real-world data offer great potential to estimate treatment effectiveness and safety, when RCTs are not available, but come with limitations. Many RWE studies, however, incur substantial bias not from data limitations or lack of randomization, but from avoidable, bias-inducing study design choices. In her talk, Dr. Bykov will present major sources of avoidable bias in RWE studies of medication safety and effectiveness and discuss potential solutions and current efforts to improve the quality of RWE studies.